Participating organisation: Centre Régional de Lutte
contre le Cancer, Montpellier
Address: Val d’Aurelle, Parc Euromédecine, 34298
Montpellier cedex 5, France
E-mail: robine@valdorel.fnclcc.fr
Objectives
Objective of participant n° 3 is to develop two synthetic indexes –
a Frailty Index and a Functional Activity Index – in order to assess
frailty and activity level of both centenarians and offspring born from
pairs of sibs having discordant / concordant phenotype as for life span.
The Frailty Index aims to assess the individual capability to cope and the
Functional Activity Index aims to assess the individual level of activity
in the daily life.
Workplan
In collaboration with participant n°4, the conceptual model of the
health outcomes will be consolidated, an operational definition of both
concepts will be set, and synthetic quantitative indexes will be defined
which summarize frailty and functional activity in order to explore the
relationships between genes and healthy/unhealthy ageing. Then the data to
be collected will be selected. Participant n° 3 will select the French
sample and collect the French data. The collaborator of participant n°3
will be formed under the supervision of participant n°4. The blood
samples collected will be sent to participant n°2.
Participant n°3 will contribute to WP1, WP2, WP4,
WP5 and to deliverables D1-D6, D8- D11.
